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7 Month Doberman Brothers with symptoms of Chronic UTIs...Please help

Question:
I am writing here because I have two 7 month old that have a problem that seems to be stumping their local vet as well as not clearly apparent to the University of Minnesota Small Animal Veterinary Clinic.

At approximately 10 weeks of age these puppies began to have blood in their urine. They were taken to the local Vet and diagnosed with UTIs (they were one week apart in showing symptoms and so this was two separate visits). Just prior to showing these symptoms they had been in a residential backyard and managed to catch and consume most of a rabbit. Their symptoms went away thru treatment with an antibiotic.

Over the course of the next 4 months one of the dogs exhibited the symptoms 4 more times and was treated with a different antibiotic each time. Each time he was treated, he would no longer have accidents in the house and stop having blood in the urine after approximately 3 pills (a day and a half).

The other puppy exhibited the symptoms 2 more times during the same 4 months and was treated the same with the same results. The local Vet was suggesting that we perform a dye test with injection into their blood stream to identify twisted or incorrectly positioned Uritors (sp). We decided to take the testing to the UofM.

Only one dog was put through any testing at this point since they are litter-mates and exhibiting identical problems.

After a Blood Profile, urine samples and general inspection, all that was determined is that the dog is 68 on the Von Willenbrand Factor scale. This was determined through sending a blood sample to Cornell University. There was no bacteria found in the bladder (extracted directly from the bladder via syringe). The diagnoses was to get the dogs neutered and watch them for any recurring signs at which point they would want to test for bacteria again and perhaps begin more testing. The dog which did not receive a checkup at the UofM is now exhibiting blood in the urine again. (He was just neutered yesterday). We did one neuter each day with the other dog being neutered today. When going to pick up the other dog (not the one with blood in the urine) we brought a urine sample in from the dog exhibiting symptoms. It was tested and found to be free of bacteria (a culture test was not done, just the more immediate form).

The local Vet has said this is out of his capacity and is now recommending that we go back to the UofM with the dogs. The UofM is wanting to do a Urine Culture of their own on the dog that has blood in the urine and is expecting to also come up negative at which point further testing would be slated. Possible conditions which have been suggested at this point are not ones which would strike both animals from a litter, but instead be more of individual defects. My concern is this, I think something is being missed and that it is going to become too costly to remedy these dogs. They are fed Nutro Max Large Breed Puppy food. They had been receiving Canola Oil mixed with their food (discontinued last week). They do not receive 'treats'. They receive bones (Shank/Knuckle) from the local Butcher which are roasted. The UofM is not anticipating to find anything even when doing the two dye tests since they say it would be so incredibly rare to find the same exact problem in brothers. If you have any other questions or would like me to expound on anything further, I am definitely available for it. Please advise if you have any ideas.


Answer:
Did you complete the antibiotic course completely each time? (gotta check).

A culture and sensitivity on urine taken via cystocentesis on a dog with symptoms may be rewarding...and not too expensive

I think I agree that malformations would be rare as you describe it. Make sure your vet at UofM explains the treatment options with all possible outcomes of the tests. Get the attending to make a student explain in detail...vet students love extra work.


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